Genome – Matt Ridley *****

The output of the human genome project is a heavy duty subject – just understanding what’s involved in the process is not easy; interpreting the results operates at a wholedifferent level. As for writing about the human genome in an accessible and enjoyable way – this is a particularly drastic challenge.

Ridley not only succeeds but does so in a rather cute fashion. This is ‘an autobiography of a species in 23 chapters’. The number 23 is no random selection – it corresponds to the number of chromosome pairs we have, and Ridley picks out a gene to feature from each chromosome pair in each chapter.

This approach enables his book to be far reaching, looking at our relationship to other owners of the gene, from bacteria to great apes, spanning from the earliest forms of life to the genes that could be responsible for intelligence and language.

Evolutionary theory, biology’s great triumph, is put across very effectively alongside good background material on genetics, and of the many books around the human genome, this has to be one of the best.

Particularly attractive is Ridley’s style – effortlessly informative, yet light enough to almost always be enjoyable. If there’s anything to criticize it is an over use of something to the effect of “to go through all of this would bore you to tears, but I just want to show you this little bit because…” – but that is a very minor moan.

This reviewer has a physics background and expects biology-based popular science to often be an necessary chore rather than a pleasure – this is a definite exception!

It’s interesting to read it alongside Andrew Brown’s In the Beginning was the Worm.

Paperback:

Kindle:

Using these links earns us commission at no cost to you

Review by Brian Clegg

Comments

Beyond Belief - Helen Pearson *****

Apparently it comes as a surprise to many that medicine was not particularly scientific until the end of the twentieth century (to be honest, it's no surprise to me - we had a GP who used homeopathy in the 90s). Instead it was based on anecdotal guidance - the kind of thing that appeared to work. Evidence-based medicine has since improved the field, trying where possible to base decisions on evidence, ideally based on randomised controlled trials. The first part of Helen Pearson's book covers this well - though I think it's by far the least interesting part of what we discover. Instead what's truly fascinating is the rest of it, looking at a wide range of other fields where evidence was rarely properly used and that are only now starting to dip a toe in the water. These include social policy, policing, conservation, business and education. The main part of the book gives us examples of how bad these areas have been in terms of basing decisions on what's always been ...

In Seach of Sea Dragons - Matthew Myerscough ****

It's common advice to would-be authors of narrative non-fiction to open with something dramatic - Matthew Myerscough certainly does this with the story of his being trapped under an avalanche on Snowdon (while his girlfriend, also carried away remains on top of the snow unhurt). It certainly is dramatic, but seemed entirely disconnected from the reason I got the book, which was to read about fossil collecting. Luckily, though, in the second chapter we get into a more conventional 'how I got interested in fossils as a boy'. Having recently reviewed Patrick Moore's autobiography and noting that astronomy was one of the few sciences where amateurs can still make a contribution, it came to mind that palaeontology is another - Myerscough is a civil engineer by trade, but just as amateur astronomers can find new details in the skies, so amateur fossil hunters have been searching for these relics for centuries. When I give talks in junior schools, the two topics that guarant...

The Infinity Machine - Sebastian Mallaby ****

It's very quickly clear that Sebastian Mallaby is a huge Demis Hassabis fan - writing about the only child prodigy and teen genius ever who was also a nice, rounded personality. After a few chapters, though, things settle down (I'm reminded of Douglas Adams' description of the Hitchhiker's Guide to the Galaxy ) and we get a good, solid trip through the journey that gave us DeepMind, their AlphaGo and AlphaFold programs, the sudden explosion of competition on the AI front and thoughts on artificial general intelligence. Although Mallaby does occasionally still go into fan mode - reading this you would think that AlphaFold had successfully perfectly predicted the structure of every protein, where it is usually not sufficiently accurate for its results to have direct practical application - we get a real feel for the way this relatively unusual company was swiftly and successfully developed away from Silicon Valley. It's readable and gives an important understanding of...

Search This Blog