Skip to main content

Magdalena Zernicka-Goetz - Four Way Interview

Photo by John Cairns
Magdalena Zernicka-Goetz is Professor of Mammalian Development and Stem Cell Biology at the University of Cambridge, and Bren Professor in Biology and Bioengineering at Caltech. She has published over 150 papers and book chapters in top scientific journals and her work on embryos won the people’s vote for scientific breakthrough of the year in Science magazine. Her new book, co-authored with Roger Highfield, is The Dance of Life: symmetry, cells and how we become human.

 Why science?

 I fell in love with biology when I was a child because I loved doing experiments and seeing what happened. It was fascinating and enormous fun. I also fell in love with art at the same time. Art and science are both based on experiments and uncovering new paths to understand the world and ourselves. Why do we think the way we think? Where do our feelings come from? Is the 'right' answer always right? Where do we come from? How do parts of our body communicate with each other?  What is the nature of time? How do our cells measure time? Can I understand it?

 I was raised in a laboratory so everyone around me was doing an experiment and asking questions.  But my passion for art is more difficult to track. It might have something to do with how I was dyslexic and yet wanted to communicate with people around me and so I started to express myself intuitively through art – mainly through abstract art and design. 

 Science and art are both imaginative and creative. They allow me to find the miraculous in everyday life.

 Why this book?

 There are many excellent popular science books. Roger Highfield and I wanted The Dance of Life to be different and to cover not only the science of how our life starts and how we build ourselves but also to be a human story, my story.  We wanted our book to be an intimate and personal account of scientific discovery.  We wanted it to talk about conflicting thoughts – devotion but also sacrifice in pursuit of science; friendship but also competition, which both dominate scientific life.  We also wanted to show the joy of discovery. 

 It was a challenge to write this book as we wrote it together – a man and a woman with different life experiences, with different schedules, with our brains working differently but we both share a passion for science, life and truth.  We were talking about some of the most complex and deepest feelings in my life and, at the same time, the most profound topics in biology, from the life of an embryo to stem cell research and the nature of our own origins. We wanted to explore what we currently understand and the limits of that understanding. We wanted to be honest in showing the life of a woman in science and the life of an immigrant. I was both and it nearly broke me at times. 

 What’s next?

 Recently I restarted my life. I moved my scientific and personal family from Cambridge (UK) to California. This last year has already been an amazing new challenge and experience. I hope some enlightenment will come from this new chapter along with the pure joy of discovery. 

 I would consider writing a second book to expand on some of the ideas in The Dance of Life to show that we should be more open and prepared to contra polarizing views about science and woman especially in science. To me, science and art are about openness, creativity, a deep way of thinking and joy that brings happiness. 

 What’s exciting you at the moment?

 My research on combining biology with engineering.  Creating embryo models from stem cells – building synthetic embryos one cell at a time - and learning answers to all of the questions that have puzzled me since I was a little girl.

 In LA, new collaborations allow me to bring new techniques in microscopy and imaging to let us see stem cells on their complex journey in embryo development, creating beautiful images that blend art with science.  Roger and I had always planned to bring even more art into The Dance of Life. 

 Every week brings a new discovery in science. If you look into the last issue of journal Nature, you can see an image from our latest paper, on an amazing mechanism that embryos develop in the second week of their life. To allow them to grow, they make holes in a membrane ‘corset‘ that originally holds them tight. How ingenious! It is great time to write about breaking boundaries, just as embryos do. 



Labels:

Comments

Post a Comment

Popular posts from this blog

God: the Science, the Evidence - Michel-Yves Bolloré and Olivier Bonnassies ***

This is, to say the least, an oddity, but a fascinating one. A translation of a French bestseller, it aims to put forward an examination of the scientific evidence for the existence of a deity… and various other things, as this is a very oddly structured book (more on that in a moment). In The God Delusion , Richard Dawkins suggested that we should treat the existence of God as a scientific claim, which is exactly what the authors do reasonably well in the main part of the book. They argue that three pieces of scientific evidence in particular are supportive of the existence of a (generic) creator of the universe. These are that the universe had a beginning, the fine tuning of natural constants and the unlikeliness of life.  To support their evidence, Bolloré and Bonnassies give a reasonable introduction to thermodynamics and cosmology. They suggest that the expected heat death of the universe implies a beginning (for good thermodynamic reasons), and rightly give the impression tha...
Post a Comment
Read more

Humble Pi - Matt Parker ****

Matt Parker had me thoroughly enjoying this collection of situations where maths and numbers go wrong in everyday life. I think the book's title is a little weak - 'Humble Pi' doesn't really convey what it's about, but that subtitle 'a comedy of maths errors' is far more informative. With his delightful conversational style, honed in his stand-up maths shows, it feels as if Parker is a friend down the pub, relating the story of some technical disaster driven by maths and computing, or regaling us with a numerical cock-up. These range from the spectacular - wobbling and collapsing bridges, for example - to the small but beautifully formed, such as Excel's rounding errors. Sometimes it's Parker's little asides that are particularly attractive. I loved his rant on why phone numbers aren't numbers at all (would it be meaningful for someone to ask you what half your phone number is?). We discover the trials and tribulations of getting cal...
Post a Comment
Read more

Quantum 2.0 - Paul Davies ****

Unlike the general theory of relativity or cosmology, quantum physics is an aspect of physics that has had a huge impact on everyday lives, particularly through the deployment of electronics, but also, for example, where superconductivity has led to practical applications. But when Paul Davies is talking about version 2.0, he is specifically describing quantum information, where quantum particles and systems are used in information technology. This obviously includes quantum computers, but Davies also brings in, for example, the potential for quantum AI technology. Quantum computers have been discussed for decades - algorithms had already been written for them as early as the 1990s - but it's only now that they are starting to become usable devices, not at the personal level but in servers. In his usual approachable style, Davies gives us four chapters bringing us up to speed on quantum basics, but then brings in quantum computing. After this we don't get solid quantum informat...
Post a Comment
Read more