Skip to main content

Magdalena Zernicka-Goetz - Four Way Interview

Photo by John Cairns
Magdalena Zernicka-Goetz is Professor of Mammalian Development and Stem Cell Biology at the University of Cambridge, and Bren Professor in Biology and Bioengineering at Caltech. She has published over 150 papers and book chapters in top scientific journals and her work on embryos won the people’s vote for scientific breakthrough of the year in Science magazine. Her new book, co-authored with Roger Highfield, is The Dance of Life: symmetry, cells and how we become human.

 Why science?

 I fell in love with biology when I was a child because I loved doing experiments and seeing what happened. It was fascinating and enormous fun. I also fell in love with art at the same time. Art and science are both based on experiments and uncovering new paths to understand the world and ourselves. Why do we think the way we think? Where do our feelings come from? Is the 'right' answer always right? Where do we come from? How do parts of our body communicate with each other?  What is the nature of time? How do our cells measure time? Can I understand it?

 I was raised in a laboratory so everyone around me was doing an experiment and asking questions.  But my passion for art is more difficult to track. It might have something to do with how I was dyslexic and yet wanted to communicate with people around me and so I started to express myself intuitively through art – mainly through abstract art and design. 

 Science and art are both imaginative and creative. They allow me to find the miraculous in everyday life.

 Why this book?

 There are many excellent popular science books. Roger Highfield and I wanted The Dance of Life to be different and to cover not only the science of how our life starts and how we build ourselves but also to be a human story, my story.  We wanted our book to be an intimate and personal account of scientific discovery.  We wanted it to talk about conflicting thoughts – devotion but also sacrifice in pursuit of science; friendship but also competition, which both dominate scientific life.  We also wanted to show the joy of discovery. 

 It was a challenge to write this book as we wrote it together – a man and a woman with different life experiences, with different schedules, with our brains working differently but we both share a passion for science, life and truth.  We were talking about some of the most complex and deepest feelings in my life and, at the same time, the most profound topics in biology, from the life of an embryo to stem cell research and the nature of our own origins. We wanted to explore what we currently understand and the limits of that understanding. We wanted to be honest in showing the life of a woman in science and the life of an immigrant. I was both and it nearly broke me at times. 

 What’s next?

 Recently I restarted my life. I moved my scientific and personal family from Cambridge (UK) to California. This last year has already been an amazing new challenge and experience. I hope some enlightenment will come from this new chapter along with the pure joy of discovery. 

 I would consider writing a second book to expand on some of the ideas in The Dance of Life to show that we should be more open and prepared to contra polarizing views about science and woman especially in science. To me, science and art are about openness, creativity, a deep way of thinking and joy that brings happiness. 

 What’s exciting you at the moment?

 My research on combining biology with engineering.  Creating embryo models from stem cells – building synthetic embryos one cell at a time - and learning answers to all of the questions that have puzzled me since I was a little girl.

 In LA, new collaborations allow me to bring new techniques in microscopy and imaging to let us see stem cells on their complex journey in embryo development, creating beautiful images that blend art with science.  Roger and I had always planned to bring even more art into The Dance of Life. 

 Every week brings a new discovery in science. If you look into the last issue of journal Nature, you can see an image from our latest paper, on an amazing mechanism that embryos develop in the second week of their life. To allow them to grow, they make holes in a membrane ‘corset‘ that originally holds them tight. How ingenious! It is great time to write about breaking boundaries, just as embryos do. 



Labels:

Comments

Post a Comment

Popular posts from this blog

Luna: Moon Rising (SF) - Ian McDonald ****

I'm not the natural audience for this book. Game of Thrones l eaves me cold - and it's hard not to feel the influence of GoT (and a whole lot of Dune )   underneath a veneer of science fiction and the trappings of a South American drug cartel in the cod-medieval family power battles and chivalric details. There are even dragons (of a sort). I'd be really sad if the future did involve this sort of throwback feudalism. However, remarkably, despite this I found Luna: Moon Rising kept me engaged. The fact is that Ian McDonald can put together a good plot with intricate machinations, which is enough to carry the reader through what can be a bewildering collection of characters. The two page scene-setter saying who did what to whom at the start was useful, but I could have done with family trees for the main family as I was constantly forgetting who was who - especially easy as McDonald endows many families with characters with the same first initial (e.g. Ariel and Al...
Post a Comment
Read more

Adventures of a Computational Explorer - Stephen Wolfram ***

Stephen Wolfram, the man behind the scientist's mathematical tool of choice, Mathematica, plus a whole host of other software products, including the uncanny Wolfram Alpha knowledge engine, is undoubtedly a genius of the first order. In this book, we get an uncensored excursion into the mind of genius - which is, without doubt, a fascinating prospect. The book consists of a collection of essays and speeches that Wolfram has produced over the last ten to fifteen years, covering an eclectic range of topics. Like all such collections, the result is something that lacks the coherence of a book with a narrative that runs through it, inevitably introducing a degree of repetition and a mix of interesting and not-so-interesting topics - but there's likely to be something to catch the attention anyone who is into computing or mathematics. One of the most interesting pieces is the opening one, where Wolfram describes being a consultant on the SF movie Arrival. He seems to hav...
Post a Comment
Read more

E=mc2: A biography of the world’s most famous equation – David Bodanis *****

David Bodanis is a storyteller, and he fulfils this role with flair in E=mc2. The premise of the book is simple – Einstein himself has been biographed (biographised?) to death, but no one has picked out this most famous of equations, dusted it down and told us what it means, where it comes from and what it has delivered. Allegedly, Bodanis was inspired to write the book after hearing see an interview with actress Cameron Diaz in which she commented that she’d really like to know what that famous collection of letters was all about. Although the book had been around for a while already when this review was written (September 2005), it seemed a very apt moment to cover it, as the equation is, as I write, exactly 100 years old. So when better to have a biography? Bodanis starts off by telling us about the individual elements of the equation. What the different letters mean, where the equal sign comes from and so on. This is entertaining, though he seems to tire of the approach on...
Post a Comment
Read more