David Linden – Four Way Interview

David J. Linden is professor of neuroscience at Johns Hopkins University School of Medicine in Maryland, USA. The author of more than ninety scientific papers and the acclaimed book The Accidental Mind, he also serves as editor-in-chief of the Journal of Neurophysiology. His latest book is Pleasure.

Why Science?

It was either that or crime and science seemed slightly less risky.

Why this book?

This book is about how the pleasure centers of the brain are activated by food, sex, meditation, exercise, drugs, gambling, paying taxes and goofing around on the Internet. It required a lot of fieldwork but I was prepared to make that sacrifice for my readers. Pleasure is the first book to explain the biology of reward in a way that will make you feel smarter and give you a laugh at the same time. Plus, it will provide you with clever anecdotes about topics from lesbian bonobo sex to the neuroscience of weight loss to hallucinogenic reindeer urine that will make you the toast of your social circle.

What’s next?

More fieldwork, I think.

What’s exciting you at the moment?

My lab has several new efforts that have me very enthused. These rely upon implanting cranial windows in the skulls of mice and then placing the mice under a special microscope (called a 2-photon confocal microscope) that allows us to see into the middle of otherwise opaque living brain tissue. This technique is allowing us to make time-lapse movies showing how neurons, glial cells and blood vessels in the brain respond to exercise and motor learning and how recovery of function proceeds following brain damage from amphetamine drugs.

Comments

The Infinite Alphabet - Cesar Hidalgo ****

Although taking a very new approach, this book by a physicist working in economics made me nostalgic for the business books of the 1980s. More on why in a moment, but Cesar Hidalgo sets out to explain how it is knowledge - how it is developed, how it is managed and forgotten - that makes the difference between success and failure. When I worked for a corporate in the 1980s I was very taken with Tom Peters' business books such of In Search of Excellence (with Robert Waterman), which described what made it possible for some companies to thrive and become huge while others failed. (It's interesting to look back to see a balance amongst the companies Peters thought were excellent, with successes such as Walmart and Intel, and failures such as Wang and Kodak.) In a similar way, Hidalgo uses case studies of successes and failures for both businesses and countries in making effective use of knowledge to drive economic success. When I read a Tom Peters book I was inspired and fired up...

God: the Science, the Evidence - Michel-Yves Bolloré and Olivier Bonnassies ***

This is, to say the least, an oddity, but a fascinating one. A translation of a French bestseller, it aims to put forward an examination of the scientific evidence for the existence of a deity… and various other things, as this is a very oddly structured book (more on that in a moment). In The God Delusion , Richard Dawkins suggested that we should treat the existence of God as a scientific claim, which is exactly what the authors do reasonably well in the main part of the book. They argue that three pieces of scientific evidence in particular are supportive of the existence of a (generic) creator of the universe. These are that the universe had a beginning, the fine tuning of natural constants and the unlikeliness of life. To support their evidence, Bolloré and Bonnassies give a reasonable introduction to thermodynamics and cosmology. They suggest that the expected heat death of the universe implies a beginning (for good thermodynamic reasons), and rightly give the impression tha...

The Giant Leap - Caleb Scharf ****

This is surely Caleb Scharf's most personal work - and certainly quite different from some of his earlier output, such as his excellent Gravity's Engines. In part this is a technological exploration of space travel, not unlike Final Frontier , but it is also about the future of humanity, more reminiscent of The Decline and Fall of the Human Empire , but with a more positive outlook. Overall, it was fascinating reading. Let's take those two aspects separately. As always, Scharf gives us plenty of meat in an approachable fashion, whether it's delving into the rocket equation, considering the pros and considerable limitations of Mars as a destination for humans (the chapter is pointedly called The Red Siren), or taking on the possibilities of asteroids. And even in the semi-technical aspect of the first Moon landing we get some more personal detail - I hadn't realised until reading this that Scharf was English by birth (being bathed in a sink at a key moment). Althou...

Search This Blog