Skip to main content

The Mould in Dr Florey’s Coat – Eric Lax ****

The intriguingly enigmatic title of this book on the development of penicillin conceals two fascinating facts. The first is Dr Florey himself. For pretty well everyone, the name associated with penicillin’s use as an antibiotic is Alexander Fleming. While Fleming does feature in this book, it’s Florey, a practically unknown name in the wider world, who is the star.
Fleming was the first to notice the anti-bacterial action of penicillin, but it took the Australian Rhodes scholar and later professor of pathology at Oxford University, Howard Florey, along with co-workers, Norman Heatley (whose practical ideas made the isolation of the active material possible) and Ernst Chain, to turn it into a practical medical weapon.
The other intriguing surprise is the coat. Apparently there was concern that Florey’s work, peaking as it did during the second world war, would be captured by invading Germans. Heatley had the idea of rubbing the penicillin mould into the four key workers lab coats, so all evidence of their work could be destroyed in the event of an invasion without losing their anti-bacterial agent.
Lax writes confidently and dives into fascinating detail of the individuals involved. Fleming emerges as a quiet-spoken but quirky individual (he delighted in creating images out of the bacteria he was growing on agar plates by arranging the initial colonies so that they would grow to form a recognisable coloured picture). Florey, despite being described as having some bluff colonial traits, comes across as a very cold man, hardly ever addressing anyone by their first name, and mostly seeming to communicate with his wife through notes. Heatley, who has been practically ignored elsewhere, is recognized at last as an essential contributor to the effort.
This is a well crafted and enjoyably paced scientific biography. As if often the case with a medical or technological breakthrough, the science itself isn’t particularly thrilling – and Lax’s expertise is very much as biographer rather than in explaining any complexities of the biology – but the implications for us all certainly make this a significant book.

Paperback:  
Using these links earns us commission at no cost to you 
Review by Brian Clegg

Comments

Popular posts from this blog

The God Game (SF) - Danny Tobey *****

Wow. I'm not sure I've ever read a book that was quite such an adrenaline rush - certainly it has been a long time since I've read a science fiction title which has kept me wanting to get back to it and read more so fiercely. 

In some ways, what we have here is a cyber-SF equivalent of Stephen King's It. A bunch of misfit American high school students face a remarkably powerful evil adversary - though in this case, at the beginning, their foe appears to be able to transform their worlds for the better.

Rather than a supernatural evil, the students take on a rogue AI computer game that thinks it is a god - and has the powers to back its belief. Playing the game is a mix of a virtual reality adventure like Pokemon Go and a real world treasure hunt. Players can get rewards for carrying out tasks - delivering a parcel, for example, which can be used to buy favours, abilities in the game and real objects. But once you are in the game, it doesn't want to let you go and is …

Uncertainty - Kostas Kampourakis and Kevin McCain ***

This is intended as a follow-on to Stuart Firestein's two books, the excellent Ignorance and its sequel, Failure, which cut through some of the myths about the nature of science and how it's not so much about facts as about what we don't know and how we search for explanations. The authors of Uncertainty do pretty much what they set out to do in explaining the significance of uncertainty and why it can make it difficult to present scientific findings to the public, who expect black-and-white facts, not grey probabilities, which can seem to some like dithering.

However, I didn't get on awfully well with the book. A minor issue was the size - it was just too physically small to hold comfortably, which was irritating. More significantly, it felt like a magazine article that was inflated to make a book. There really was only one essential point made over and over again, with a handful of repeated examples. I want something more from a book - more context and depth - that …

Where are the chemistry popular science books?

by Brian Clegg
There has never been more emphasis on the importance of public engagement. We need both to encourage a deeper interest in science and to counter anti-scientific views that seem to go hand-in-hand with some types of politics. Getting the public interested in science both helps recruit new scientists of the future and spreads an understanding of why an area of scientific research deserves funding. Yet it is possible that chemistry lags behind the other sciences in outreach. As a science writer, and editor of this website, I believe that chemistry is under-represented in popular science. I'd like to establish if this is the case, if so why it is happening - and what can be done to change things. 


An easy straw poll is provided by the topic tags on the site. At the time of writing, there are 22 books under 'chemistry' as opposed to 97 maths, 126 biology and 182 physics. The distribution is inevitably influenced by editorial bias - but as the editor, I can confirm …